Pharmaceutical intermediates

Drug intermediates -Pharmaceutical intermediates: A material that is produced during a process step of the drug substance and must undergo further molecular changes or refining before it becomes a drug substance. The intermediates can be separated or not separated.

Active Pharmaceutical Ingredient (APIS)(or Drug Substance) : Active Pharmaceutical Ingredient (API)(or Drug Substance) : Any substance or mixture of substances intended to be used in the manufacture of pharmaceutical products and, when used in pharmaceutical products, to be an active ingredient in pharmaceutical products. Such substances have pharmacological activity or other direct effects in the diagnosis, treatment, symptom relief, management or prevention of disease, or can affect the function and structure of the body. As can be seen from the definition, the Intermediates APIS is a key product of the previous process of manufacturing the API and has a different structure from the API

Finally, for example, amoxicillin capsules are called preparations, amoxicillin is called APIS, and 6-APA is called Veterinary Intermediates APIS.

 Penicillin potassium for injection is called preparation, penicillin potassium is called Veterinary raw materials, and green potassium industrial salt is called intermediate